Fourth generation · W220 · 2000–2006

2005Mercedes-Benz S-Class


A lighter, sleeker S-Class with Airmatic air suspension, Distronic radar cruise, and the Pre-Safe pre-collision system (2002). Topped by the bi-turbo V12 S 600 and AMG S 65. US model years 2000–2006.

Fourth generation · W220

2001–2005 Mercedes-Benz S 600 (W220), photographed from the side

Photo: “Mercedes-Benz S-Class -- 06-22-2009.jpg” by IFCAR / Wikimedia CommonsPublic domain

Start here

What do you need to know?

This page covers the whole 2005 Mercedes-Benz S-Class model year. Choose your task first; exact trims and engines are separated where the factory offered different versions.

Complete, source-verified lineup

Find your exact 2005 S-Class

Start with a family, body style, or engine. Every card opens the facts and maintenance information for that factory version.

7factory configurations
Verified complete for the U.S.-marketHow this lineup was verified

We checked this U.S.-market lineup against period sources for factory sedan, coupe, cabriolet, drivetrain, and powertrain roster represented by the cited exact-year or factory-archive evidence. Every version shown below has its own detail page.

Verified 2026-09-01 from Mercedes-Benz USA — model year 2005 S-Class sales presentation guide.

7versions shown
Four-door rear-wheel drive luxury sedan

Mercedes-Benz S 430 Automatic

Body
Four-door rear-wheel drive luxury sedan
Engine
4.3-liter M113 V8
Gearbox
7-speed automatic
Built
Regular production
Open exact version
Four-door 4MATIC all-wheel drive luxury sedan

Mercedes-Benz S 430 4MATIC Automatic

Body
Four-door 4MATIC all-wheel drive luxury sedan
Engine
4.3-liter M113 V8
Gearbox
5-speed automatic
Built
Regular production
Open exact version
Four-door rear-wheel drive luxury sedan

Mercedes-Benz S 500 Automatic

Body
Four-door rear-wheel drive luxury sedan
Engine
5.0-liter M113 V8
Gearbox
7-speed automatic
Built
Regular production
Open exact version
Four-door 4MATIC all-wheel drive luxury sedan

Mercedes-Benz S 500 4MATIC Automatic

Body
Four-door 4MATIC all-wheel drive luxury sedan
Engine
5.0-liter M113 V8
Gearbox
5-speed automatic
Built
Regular production
Open exact version
Four-door rear-wheel drive luxury sedan

Mercedes-Benz S 55 AMG Automatic

Body
Four-door rear-wheel drive luxury sedan
Engine
5.4-liter supercharged AMG V8
Gearbox
5-speed automatic
Built
Regular production
Open exact version
Four-door rear-wheel drive luxury sedan

Mercedes-Benz S 600 Automatic

Body
Four-door rear-wheel drive luxury sedan
Engine
5.5-liter twin-turbo M275 V12
Gearbox
5-speed automatic
Built
Regular production
Open exact version
Four-door rear-wheel drive luxury sedan

Mercedes-Benz S 65 AMG Automatic

Body
Four-door rear-wheel drive luxury sedan
Engine
6.0-liter twin-turbo AMG V12
Gearbox
5-speed automatic
Built
Regular production
Open exact version

The 2005 model year

Overview

The 2005 U.S. W220 lineup retained both drivetrains for the S 430 and S 500, the S 55 AMG, and the S 600, then added the 604-hp S 65 AMG early in 2005. Mercedes-Benz USA's own guides distinguish the S 65 as a separate twin-turbo V12 model rather than an appearance package.

Specifications

Engines
  • 4.3-liter M113 V8
  • 5.0-liter M113 V8
  • 5.4-liter supercharged AMG V8
  • 5.5-liter twin-turbo M275 V12
  • 6.0-liter twin-turbo AMG V12
Transmissions
7-speed automatic, 5-speed automatic
Body styles
Four-door rear-wheel drive luxury sedan, Four-door 4MATIC all-wheel drive luxury sedan

Year over year

What changed

  • The S 65 AMG joined as the seven-model range's new performance flagship.
  • Mercedes-Benz offered 4MATIC as a no-charge alternative on S 430 and S 500 models while retaining their rear-drive configurations.

Worth knowing

Notable

  • The S 65's engine, transmission, brakes, and service demands require a dedicated configuration page.

Living with it

Reliability & ownership notes

  • Inspect the individual car's Airmatic or optional Active Body Control system, electronics, corrosion condition, and documented service history; generation reputation is not proof of a fault on every car.
  • Match filters, ignition parts, fluids, transmission service parts, and suspension components to the exact engine, drivetrain, chassis number, and build date before ordering.

Maintenance & service parts

Keep your 2005 S-Class on the road

Start with the service interval, then match the engine or exact version you own. Order links appear only when a catalog-backed part number is available, and every listing still needs a fitment check.

Service desk

What this car needs & when

Use this as a service-planning checklist for 2005 Mercedes-Benz S-Class. Start with the interval, confirm which engine or configuration you have, then use an exact ordering reference when one is verified.

Service topics
6
Factory intervals
6
Fitment-scoped
6
Exact references
1

Before orderingIdentify your engine, options and build date.Part numbers and sizes can change within one model year. Shopping links appear only for catalog-backed references; still verify the listing against your vehicle before ordering.

Collect

Bring this model year home

Find a scale model using the exact year, make, and model—not a generic generation search.

Sources

  1. Mercedes-Benz Media — factory S-Class history and W126 design/safety chronology
  2. Mercedes-Benz Public Archive — 220-series S-Class model history
  3. Mercedes-Benz USA — model year 2005 S-Class sales presentation guide
  4. Mercedes-Benz USA — model year 2006 S-Class sales presentation guide

Other Fourth generation years

All Fourth generation · W220 years →

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