Fourth generation · W220 · 2000–2006

2000Mercedes-Benz S-Class


A lighter, sleeker S-Class with Airmatic air suspension, Distronic radar cruise, and the Pre-Safe pre-collision system (2002). Topped by the bi-turbo V12 S 600 and AMG S 65. US model years 2000–2006.

Fourth generation · W220

2000 Mercedes-Benz S-Class (W220) — sedan, front three-quarter view

Photo: “Mercedes-Benz W220 S320 2000” by Ethan Llamas / Wikimedia Commons, licensed under CC BY-SA 4.0. Cropped to 16:9.

Start here

What do you need to know?

This page covers the whole 2000 Mercedes-Benz S-Class model year. Choose your task first; exact trims and engines are separated where the factory offered different versions.

Complete, source-verified lineup

Find your exact 2000 S-Class

Start with a family, body style, or engine. Every card opens the facts and maintenance information for that factory version.

2factory configurations
Verified complete for the U.S.-marketHow this lineup was verified

We checked this U.S.-market lineup against period sources for factory sedan, coupe, cabriolet, drivetrain, and powertrain roster represented by the cited exact-year or factory-archive evidence. Every version shown below has its own detail page.

Verified 2026-09-01 from Mercedes-Benz Public Archive — 220-series S-Class model history, Mercedes-Benz USA — model year 2006 S-Class sales presentation guide.

2versions shown

The 2000 model year

Overview

The W220 reached U.S. showrooms for model year 2000 as a smaller, lighter successor to the W140. The U.S. sedan range opened with long-wheelbase S 430 and S 500 V8 models; Mercedes-Benz's own 2006 retrospective identifies the 2000 launch as the beginning of the W220-series U.S. run.

Specifications

Engines
  • 4.3-liter M113 V8
  • 5.0-liter M113 V8
Transmissions
5-speed automatic
Body styles
Four-door rear-wheel drive luxury sedan

Year over year

What changed

  • An all-new W220 body replaced the final W140 sedans.
  • Airmatic air suspension, COMAND, and available Distronic established the generation's chassis and electronics baseline.

Worth knowing

Notable

  • This page follows U.S. model years: production began during 1999, but the first U.S. catalog year is 2000.

Living with it

Reliability & ownership notes

  • Inspect the individual car's Airmatic or optional Active Body Control system, electronics, corrosion condition, and documented service history; generation reputation is not proof of a fault on every car.
  • Match filters, ignition parts, fluids, transmission service parts, and suspension components to the exact engine, drivetrain, chassis number, and build date before ordering.

Maintenance & service parts

Keep your 2000 S-Class on the road

Start with the service interval, then match the engine or exact version you own. Order links appear only when a catalog-backed part number is available, and every listing still needs a fitment check.

Service desk

What this car needs & when

Use this as a service-planning checklist for 2000 Mercedes-Benz S-Class. Start with the interval, confirm which engine or configuration you have, then use an exact ordering reference when one is verified.

Service topics
7
Factory intervals
7
Fitment-scoped
7
Exact references
1

Before orderingIdentify your engine, options and build date.Part numbers and sizes can change within one model year. Shopping links appear only for catalog-backed references; still verify the listing against your vehicle before ordering.

  • Engine oil and filter

    Sourced interval available

    Applies to: 2000 · M113.960 5.0L V8 · S 500 sedan (220.175) · United States · Exact 2000 S 500 (220.175) factory record; S 430, S 600, 4MATIC, and other W220 configurations are not claimed.

    Published interval: 10,000 mi / 15,000 km / 12 months · At each FSS-indicated A or B service; operating conditions can shorten the interval. The factory reset reference is 10,000 miles/365 days.

    Source: Mercedes-Benz — 2000 S 500 (W220/M113) FSS schedule, preserved by Operation CHARM · Service A and B schedules; FSS description — oil/filter at both services and 10,000-mile/365-day reset reference · checked

  • Dust filter

    Sourced interval available

    Applies to: 2000 · M113.960 5.0L V8 · S 500 sedan (220.175) · United States · Exact 2000 S 500 (220.175) factory record; S 430, S 600, 4MATIC, and other W220 configurations are not claimed.

    Published interval: 10,000 mi / 15,000 km / 12 months · At each FSS-indicated A or B service; operating conditions can shorten the interval.

    Source: Mercedes-Benz — 2000 S 500 (W220/M113) FSS schedule, preserved by Operation CHARM · Service A and B schedules — replace dust filter · checked

  • Brake fluid

    Sourced interval available

    Applies to: 2000 · M113.960 5.0L V8 · S 500 sedan (220.175) · United States · Exact 2000 S 500 (220.175) factory record; S 430, S 600, 4MATIC, and other W220 configurations are not claimed.

    Published interval: 24 months · Replace every two years.

    Source: Mercedes-Benz — 2000 S 500 (W220/M113) FSS schedule, preserved by Operation CHARM · Supplemental Service Items — Every 2 Years · checked

  • Engine air-filter element

    Exact reference available

    Applies to: 2000 · M113.960 5.0L V8 · S 500 sedan (220.175) · United States · Exact 2000 S 500 (220.175) factory record; S 430, S 600, 4MATIC, and other W220 configurations are not claimed.

    Published interval: 60,000 mi / 96,000 km / 48 months · Approximately; whichever comes first.

    Source: Mercedes-Benz — 2000 S 500 (W220/M113) FSS schedule, preserved by Operation CHARM · Supplemental Service Items — Every 60,000 miles or 4 Years · checked

    S 430 — 4.3-liter M113 V8

    K&N 33-2181

    Applies to: 2000 · 4.3-liter M113 V8 · S 430 · Exact 2000 S 430 engine application. Confirm VIN and build date before ordering.

    Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W220 S-Class table — S 430, 2000 — 33-2181 (two required) · checked

    Verified ordering references

    S 500 — 5.0-liter M113 V8

    K&N 33-2181

    Applies to: 2000 · 5.0-liter M113 V8 · S 500 · Exact 2000 S 500 engine application. Confirm VIN and build date before ordering.

    Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W220 S-Class table — S 500, 2000 — 33-2181 (two required) · checked

    Verified ordering references

  • Fuel filter

    Sourced interval available

    Applies to: 2000 · M113.960 5.0L V8 · S 500 sedan (220.175) · United States · Exact 2000 S 500 (220.175) factory record; S 430, S 600, 4MATIC, and other W220 configurations are not claimed.

    Published interval: 60,000 mi / 96,000 km / 60 months · Approximately; whichever comes first.

    Source: Mercedes-Benz — 2000 S 500 (W220/M113) FSS schedule, preserved by Operation CHARM · Supplemental Service Items — Every 60,000 miles or 5 Years · checked

  • Spark plugs

    Sourced interval available

    Applies to: 2000 · M113.960 5.0L V8 · S 500 sedan (220.175) · United States · Exact 2000 S 500 (220.175) factory record; S 430, S 600, 4MATIC, and other W220 configurations are not claimed.

    Published interval: 100,000 mi / 160,000 km / 60 months · Approximately; whichever comes first.

    Source: Mercedes-Benz — 2000 S 500 (W220/M113) FSS schedule, preserved by Operation CHARM · Supplemental Service Items — Every 100,000 miles or 5 Years · checked

  • Recirculated-air and activated-charcoal prefilters

    Sourced interval available

    Applies to: 2000 · M113.960 5.0L V8 · S 500 sedan (220.175) · United States · Exact 2000 S 500 (220.175) factory record; S 430, S 600, 4MATIC, and other W220 configurations are not claimed.

    Published interval: 45,000 mi / 72,000 km / 24 months · Approximately; whichever comes first.

    Source: Mercedes-Benz — 2000 S 500 (W220/M113) FSS schedule, preserved by Operation CHARM · Supplemental Service Items — Every 45,000 Miles or 2 Years · checked

Collect

Bring this model year home

Find a scale model using the exact year, make, and model—not a generic generation search.

Sources

  1. Mercedes-Benz Media — factory S-Class history and W126 design/safety chronology
  2. Mercedes-Benz Public Archive — 220-series S-Class model history
  3. Mercedes-Benz USA — model year 2006 S-Class sales presentation guide

Other Fourth generation years

All Fourth generation · W220 years →

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