Car Model History

Seventh generation · W223 · 2021–present

2021Mercedes-Benz S-Class

The current S-Class — sedan only — with up to five screens, an augmented-reality head-up display, rear-seat airbags, and the plug-in-hybrid S 63 E Performance V8. No coupe or convertible successor is planned.

Seventh generation · W223

2021 Mercedes-Benz S-Class (W223) — sedan, front three-quarter view

Photo: “Mercedes-Benz S-Klasse (W223) S 580 e (2021) (53323040439)” by Charles from Port Chester, New York / Wikimedia Commons, licensed under CC BY 2.0. Cropped to 16:9.

Start here

What do you need to know?

This page covers the whole 2021 Mercedes-Benz S-Class model year. Choose your task first; exact trims and engines are separated where the factory offered different versions.

Complete, source-verified lineup

Find your exact 2021 S-Class

Start with a family, body style, or engine. Every card opens the facts and maintenance information for that factory version.

2factory configurations
Verified complete for the U.S.-marketHow this lineup was verified

We checked this U.S.-market lineup against period sources for factory sedan, coupe, cabriolet, drivetrain, and powertrain roster represented by the cited exact-year or factory-archive evidence. Every version shown below has its own detail page.

Verified 2026-09-01 from Mercedes-Benz Public Archive — 223-series S-Class model history.

2versions shown
Four-door 4MATIC all-wheel drive luxury sedan

Mercedes-Benz S 500 4MATIC Automatic

Body
Four-door 4MATIC all-wheel drive luxury sedan
Engine
3.0-liter turbocharged inline-six mild hybrid
Gearbox
9-speed automatic
Built
Regular production
Open exact version
Four-door 4MATIC all-wheel drive luxury sedan

Mercedes-Benz S 580 4MATIC Automatic

Body
Four-door 4MATIC all-wheel drive luxury sedan
Engine
4.0-liter twin-turbo V8 mild hybrid
Gearbox
9-speed automatic
Built
Regular production
Open exact version

The 2021 model year

Overview

The seventh-generation W223 arrived for 2021 as a sedan-only flagship, doubling down on technology with up to five screens, an augmented-reality head-up display, rear-axle steering, and the first production rear-seat airbags. No coupe or convertible successor accompanied the new sedan.

Specifications

Body styles
Sedan

Year over year

What changed

  • Sedan-only W223 with up to five displays and an AR head-up display.
  • First production rear-seat airbags; the preceding S-Class coupe and cabriolet were not replaced.

Worth knowing

Notable

  • The current S-Class; the two-door body styles were not given a successor.

Living with it

Reliability & ownership notes

  • A current-generation car; standard new-vehicle service and software-update considerations apply.

Maintenance & service parts

Keep your 2021 S-Class on the road

Start with the service interval, then match the engine or exact version you own. Order links appear only when a catalog-backed part number is available, and every listing still needs a fitment check.

Service desk

What this car needs & when

Use this as a service-planning checklist for 2021 Mercedes-Benz S-Class. Start with the interval, confirm which engine or configuration you have, then use an exact ordering reference when one is verified.

Service topics
9
Factory intervals
9
Fitment-scoped
9
Exact references
1

Before orderingIdentify your engine, options and build date.Part numbers and sizes can change within one model year. Shopping links appear only for catalog-backed references; still verify the listing against your vehicle before ordering.

  • Synthetic engine oil and filter

    Sourced interval available

    Applies to: 2021 · United States · Mercedes-Benz's September 2021 dealer guide labels this table for model year 2015 to present; this record uses it only through the guide's publication model year.

    Published interval: 10,000 mi / 16,000 km / 12 months · Every listed annual/10,000-mile service.

    Source: Mercedes-Benz USA service-and-warranty library — select 2021 S-Class · PDF page 5 — All Models: synthetic motor oil and filter replacement at 10,000-mile/one-year increments · checked

  • Activated-charcoal combination and dust filters

    Sourced interval available

    Applies to: 2021 · United States · Mercedes-Benz's September 2021 dealer guide labels this table for model year 2015 to present; this record uses it only through the guide's publication model year.

    Published interval: 20,000 mi / 32,000 km / 24 months · Both published filter rows repeat at 20,000-mile/two-year increments.

    Source: Mercedes-Benz USA service-and-warranty library — select 2021 S-Class · PDF page 5 — All Models: activated-charcoal combination filter and dust-filter rows · checked

  • Brake fluid

    Sourced interval available

    Applies to: 2021 · United States · Mercedes-Benz's September 2021 dealer guide labels this table for model year 2015 to present; this record uses it only through the guide's publication model year.

    Published interval: 20,000 mi / 32,000 km / 24 months · Whichever comes first.

    Source: Mercedes-Benz USA service-and-warranty library — select 2021 S-Class · PDF page 5 — All Models: brake-fluid change at 20,000-mile/two-year increments · checked

  • Spark plugs

    Sourced interval available

    Applies to: 2021 · Gasoline engines · United States · Mercedes-Benz's September 2021 dealer guide labels this table for model year 2015 to present; this record uses it only through the guide's publication model year.

    Published interval: 50,000 mi / 80,000 km / 60 months · Base all-model prepaid-maintenance row; vehicle-specific exceptions require the VIN-specific maintenance record.

    Source: Mercedes-Benz USA service-and-warranty library — select 2021 S-Class · PDF page 5 — All Models: spark-plug replacement at 50,000 miles/5 years and 100,000 miles/10 years · checked

  • Engine air filter

    Exact reference available

    Applies to: 2021 · United States · Mercedes-Benz's September 2021 dealer guide labels this table for model year 2015 to present; this record uses it only through the guide's publication model year.

    Published interval: 50,000 mi / 80,000 km / 60 months · Base all-model prepaid-maintenance row.

    Source: Mercedes-Benz USA service-and-warranty library — select 2021 S-Class · PDF page 5 — All Models: engine air-filter replacement at 50,000 miles/5 years and 100,000 miles/10 years · checked

    Mercedes-AMG models

    Applies to: 2021 · Mercedes-AMG S-Class · United States · Mercedes-Benz's September 2021 dealer guide labels this table for model year 2015 to present; this record uses it only through the guide's publication model year.

    Published interval: 30,000 mi / 48,000 km / 36 months · Specific AMG-model service row.

    Source: Mercedes-Benz USA service-and-warranty library — select 2021 S-Class · PDF page 5 — Specific AMG Model Services: engine air filter at 30,000-mile/3-year increments · checked

    S 500 4MATIC — 3.0-liter turbocharged inline-six mild hybrid

    K&N 33-3068

    Applies to: 2021 · 3.0-liter turbocharged inline-six mild hybrid · S 500 4MATIC · Exact 2021 S 500 4MATIC engine application. Confirm VIN and build date before ordering.

    Source: K&N Engineering — Mercedes-Benz S-Class replacement-air-filter application catalog · 2021 Mercedes-Benz S500 3.0L inline-six Gas — 33-3068 · checked

    Verified ordering references

    S 580 4MATIC — 4.0-liter twin-turbo V8 mild hybrid

    K&N 33-3183

    Applies to: 2021 · 4.0-liter twin-turbo V8 mild hybrid · S 580 4MATIC · Exact 2021 S 580 4MATIC engine application. Confirm VIN and build date before ordering.

    Source: K&N Engineering — Mercedes-Benz S-Class replacement-air-filter application catalog · 2021 Mercedes-Benz S580 4.0L V8 Gas — 33-3183 (two per package) · checked

    Verified ordering references

  • Automatic-transmission oil and filter

    Sourced interval available

    Applies to: 2021 · United States · Mercedes-Benz's September 2021 dealer guide labels this table for model year 2015 to present; this record uses it only through the guide's publication model year.

    Published interval: 60,000 mi / 96,000 km / 72 months · Base all-model prepaid-maintenance row.

    Source: Mercedes-Benz USA service-and-warranty library — select 2021 S-Class · PDF page 5 — All Models: transmission oil and filter at 60,000 miles/6 years · checked

    Mercedes-AMG models

    Applies to: 2021 · Mercedes-AMG S-Class · United States · Mercedes-Benz's September 2021 dealer guide labels this table for model year 2015 to present; this record uses it only through the guide's publication model year.

    Published interval: 30,000 mi / 48,000 km / 36 months · Specific AMG-model service row.

    Source: Mercedes-Benz USA service-and-warranty library — select 2021 S-Class · PDF page 5 — Specific AMG Model Services: transmission oil and filter at 30,000-mile/3-year increments · checked

  • Main-circuit coolant

    Sourced interval available

    Applies to: 2021 · V12 · United States · Mercedes-Benz's September 2021 dealer guide labels this table for model year 2015 to present; this record uses it only through the guide's publication model year.

    Published interval: 30,000 mi / 48,000 km / 36 months · V12 models only.

    Source: Mercedes-Benz USA service-and-warranty library — select 2021 S-Class · PDF page 5 — Specific Model Services: V12 main-circuit coolant at 30,000-mile/3-year increments · checked

  • Rear-axle oil

    Sourced interval available

    Applies to: 2021 · Mercedes-AMG S-Class · United States · Mercedes-Benz's September 2021 dealer guide labels this table for model year 2015 to present; this record uses it only through the guide's publication model year.

    Published interval: 30,000 mi / 48,000 km / 36 months · Mercedes-AMG models; the table also calls for an initial 2,000-mile change.

    Source: Mercedes-Benz USA service-and-warranty library — select 2021 S-Class · PDF page 5 — Specific AMG Model Services: rear-axle oil at 2,000 miles, then 30,000-mile/3-year increments · checked

    Initial AMG rear-axle service

    Applies to: 2021 · Mercedes-AMG S-Class · United States · Mercedes-Benz's September 2021 dealer guide labels this table for model year 2015 to present; this record uses it only through the guide's publication model year.

    Published interval: 2,000 mi / 3,200 km · Initial service.

    Source: Mercedes-Benz USA service-and-warranty library — select 2021 S-Class · PDF page 5 — Specific AMG Model Services: initial rear-axle oil change at 2,000 miles · checked

  • Poly-V-belt

    Sourced interval available

    Applies to: 2021 · United States · Mercedes-Benz's September 2021 dealer guide labels this table for model year 2015 to present; this record uses it only through the guide's publication model year.

    Published interval: 60,000 mi / 96,000 km / 72 months · Specific-model service; confirm applicability by VIN.

    Source: Mercedes-Benz USA service-and-warranty library — select 2021 S-Class · PDF page 5 — Specific Model Services: replace poly-V-belt at 60,000 miles/6 years · checked

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Sources

  1. Wikipedia — "Mercedes-Benz S-Class"

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