Sixth generation · W222 · 2014–2020

2016Mercedes-Benz S-Class

A technology landmark: Magic Body Control's road-scanning suspension and an all-LCD cabin. Reintegrated the two-door as the S-Class Coupé (C217) and added the first S-Class Cabriolet (A217); the Mercedes-Maybach S-Class revived the Maybach name in 2015. US model years 2014–2020.

Sixth generation · W222

Photo: “2016 Mercedes-Benz S 350 d (W 222) sedan (2016-03-05) 03” by EurovisionNim / Wikimedia Commons, licensed under CC BY-SA 4.0. Cropped to 16:9.

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What do you need to know?

This page covers the whole 2016 Mercedes-Benz S-Class model year. Choose your task first; exact trims and engines are separated where the factory offered different versions.

Complete, source-verified lineup

Find your exact 2016 S-Class

Start with a family, body style, or engine. Every card opens the facts and maintenance information for that factory version.

10factory configurations

Verified complete for the U.S.-marketHow this lineup was verified

We checked this U.S.-market lineup against period sources for factory sedan, coupe, cabriolet, drivetrain, and powertrain roster represented by the cited exact-year or factory-archive evidence. Every version shown below has its own detail page.

Verified 2026-09-01 from Mercedes-Benz USA — 2016 S-Class Sedan brochure specification tables, Mercedes-Benz USA — 2016 S-Class Coupe brochure specification tables, Mercedes-Benz USA — Model Year 2016 Service and Warranty Information model matrix.

Four-door rear-wheel-drive sedan

Mercedes-Benz S 550 Sedan

Body: Four-door rear-wheel-drive sedan
Engine: 4.7-liter biturbo V8 (449 hp)
Gearbox: 7-speed automatic
Built: Regular production

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Four-door all-wheel-drive sedan

Mercedes-Benz S 550 4MATIC Sedan

Body: Four-door all-wheel-drive sedan
Engine: 4.7-liter biturbo V8 (449 hp)
Gearbox: 7-speed automatic
Built: Regular production

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Four-door rear-wheel-drive plug-in-hybrid sedan

Mercedes-Benz S 550e Sedan

Body: Four-door rear-wheel-drive plug-in-hybrid sedan
Engine: 3.0-liter biturbo V6 plug-in hybrid (436 hp combined)
Gearbox: 7G-TRONIC 7-speed automatic
Built: Regular production

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Four-door rear-wheel-drive sedan

Mercedes-Benz S 600 Sedan

Body: Four-door rear-wheel-drive sedan
Engine: 6.0-liter biturbo V12 (523 hp)
Gearbox: 7G-TRONIC 7-speed automatic
Built: Regular production

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Four-door performance all-wheel-drive sedan

Mercedes-AMG S 63 Sedan

Body: Four-door performance all-wheel-drive sedan
Engine: Handcrafted 5.5-liter biturbo AMG V8 (577 hp)
Gearbox: AMG SPEEDSHIFT MCT 7-speed
Built: Regular production

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Four-door rear-wheel-drive performance sedan

Mercedes-AMG S 65 Sedan

Body: Four-door rear-wheel-drive performance sedan
Engine: Handcrafted 6.0-liter biturbo AMG V12 (621 hp)
Gearbox: AMG SPEEDSHIFT PLUS 7G-TRONIC 7-speed
Built: Regular production

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Four-door long-wheelbase rear-wheel-drive sedan

Mercedes-Maybach S 600

Body: Four-door long-wheelbase rear-wheel-drive sedan
Engine: 6.0-liter biturbo V12 (523 hp)
Gearbox: 7G-TRONIC 7-speed automatic
Built: Regular production

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Two-door all-wheel-drive coupe

Mercedes-Benz S 550 4MATIC Coupe

Body: Two-door all-wheel-drive coupe
Engine: 4.7-liter biturbo V8 (449 hp)
Gearbox: 7-speed automatic
Built: Regular production

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Two-door performance all-wheel-drive coupe

Mercedes-AMG S 63 Coupe

Body: Two-door performance all-wheel-drive coupe
Engine: Handcrafted 5.5-liter biturbo AMG V8 (577 hp)
Gearbox: AMG SPEEDSHIFT MCT 7-speed
Built: Regular production

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Two-door rear-wheel-drive performance coupe

Mercedes-AMG S 65 Coupe

Body: Two-door rear-wheel-drive performance coupe
Engine: Handcrafted 6.0-liter biturbo AMG V12 (621 hp)
Gearbox: AMG SPEEDSHIFT PLUS 7G-TRONIC 7-speed
Built: Regular production

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The 2016 model year

Overview

Mercedes-Benz USA's 2016 sedan and coupe brochures plus its exact-year warranty model matrix establish 10 U.S. S-Class configurations: six regular sedans, three coupes, and the Mercedes-Maybach S 600. The S 550 sedan split into rear- and all-wheel-drive applications, while the coupe range paired one S 550 4MATIC with AMG S 63 and rear-drive V12 AMG S 65 models.

Specifications

Engines: 4.7-liter biturbo V8 (449 hp)
3.0-liter biturbo V6 plug-in hybrid (436 hp combined)
6.0-liter biturbo V12 (523 hp)
Handcrafted 5.5-liter biturbo AMG V8 (577 hp)
Handcrafted 6.0-liter biturbo AMG V12 (621 hp)
Transmissions: 7-speed automatic, 7G-TRONIC 7-speed automatic, AMG SPEEDSHIFT MCT 7-speed, AMG SPEEDSHIFT PLUS 7G-TRONIC 7-speed
Body styles: Four-door rear-wheel-drive sedan, Four-door all-wheel-drive sedan, Four-door rear-wheel-drive plug-in-hybrid sedan, Four-door performance all-wheel-drive sedan, Four-door rear-wheel-drive performance sedan, Four-door long-wheelbase rear-wheel-drive sedan, Two-door all-wheel-drive coupe, Two-door performance all-wheel-drive coupe, Two-door rear-wheel-drive performance coupe

Year over year

What changed

The S 550e plug-in hybrid joined the U.S. sedan specification table with a 436-hp combined rating.
The 2016 U.S. roster did not yet include the S-Class Cabriolet or the later Mercedes-Maybach S 550 4MATIC.

Worth knowing

Notable

Four of the ten verified applications are outside the regular sedan roster: three coupes and the extended-wheelbase Mercedes-Maybach S 600.

Living with it

Reliability & ownership notes

Verify suspension, cooling, electronics, and recall history on every body; inspect high-voltage service history on the S 550e and extra rear-cabin systems on the Mercedes-Maybach.
Match filters, fluids, brakes, tires, ignition, and driveline service to the exact V8, V12, hybrid, AMG, body, and drivetrain application.

Maintenance & service parts

Keep your 2016 S-Class on the road

Start with the service interval, then match the engine or exact version you own. Order links appear only when a catalog-backed part number is available, and every listing still needs a fitment check.

Service topics: 5
Factory intervals: 5
Fitment-scoped: 5
Exact references: 1

Before orderingIdentify your engine, options and build date.Part numbers and sizes can change within one model year. Shopping links appear only for catalog-backed references; still verify the listing against your vehicle before ordering.

Engine oil and filter
Sourced interval available
Applies to: 2016 · United States
Published interval: 10,000 mi / 16,000 km / 12 months · First Service A; thereafter at each alternating A/B service, or earlier when ASSYST PLUS indicates.
Source: Mercedes-Benz USA — 2016 Maintenance Booklet · pages 7 and 10 — Service A/B intervals and oil/filter row · checked 2026-08-05
Brake fluid
Sourced interval available
Applies to: 2016 · United States
Published interval: 24 months · Replace every two years.
Source: Mercedes-Benz USA — 2016 Maintenance Booklet · page 17 — additional maintenance work · checked 2026-08-05
Engine air filter
Exact reference available
Applies to: 2016 · M276, M278 · United States
Published interval: 50,000 mi / 80,000 km / 60 months · Whichever comes first.
Source: Mercedes-Benz USA — 2016 Maintenance Booklet · page 18 — engine 276/278 air-filter row · checked 2026-08-05
AMG M157 or V12 M279
Applies to: 2016 · M157, M279 · United States
Published interval: 30,000 mi / 48,000 km / 36 months · Whichever comes first.
Source: Mercedes-Benz USA — 2016 Maintenance Booklet · page 18 — engine 157/279 air-filter row · checked 2026-08-05
S 550 — 4.7-liter biturbo V8 (449 hp)
K&N 33-2474
Applies to: 2016 · 4.7-liter biturbo V8 (449 hp) · S 550 · Exact 2016 S 550 engine application. Confirm VIN and build date before ordering.
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 550, 2016 — 33-2474 (two required) · checked 2026-09-01
Verified ordering references
- Service replacementK&N 33-2474
  Qty. 2 · Reusable engine air-filter element · catalog-listed
  K&N lists two elements for this application; confirm VIN and build date before ordering.
  Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 550, 2016 — 33-2474 (two required) · checked 2026-09-01
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S 550 4MATIC — 4.7-liter biturbo V8 (449 hp)
K&N 33-2474
Applies to: 2016 · 4.7-liter biturbo V8 (449 hp) · S 550 4MATIC · Exact 2016 S 550 4MATIC engine application. Confirm VIN and build date before ordering.
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 550 4MATIC, 2016 — 33-2474 (two required) · checked 2026-09-01
Verified ordering references
- Service replacementK&N 33-2474
  Qty. 2 · Reusable engine air-filter element · catalog-listed
  K&N lists two elements for this application; confirm VIN and build date before ordering.
  Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 550 4MATIC, 2016 — 33-2474 (two required) · checked 2026-09-01
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S 550e — 3.0-liter biturbo V6 plug-in hybrid (436 hp combined)
K&N 33-2985
Applies to: 2016 · 3.0-liter biturbo V6 plug-in hybrid (436 hp combined) · S 550e · Exact 2016 S 550e engine application. Confirm VIN and build date before ordering.
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222 S-Class table — S 550e, 2016 — 33-2985 · checked 2026-09-01
Verified ordering references
- Service replacementK&N 33-2985
  Qty. 1 · Reusable engine air-filter element · catalog-listed
  K&N lists one element for this application; confirm VIN and build date before ordering.
  Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222 S-Class table — S 550e, 2016 — 33-2985 · checked 2026-09-01
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S 600 — 6.0-liter biturbo V12 (523 hp)
K&N 33-2412
Applies to: 2016 · 6.0-liter biturbo V12 (523 hp) · S 600 · Exact 2016 S 600 engine application. Confirm VIN and build date before ordering.
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222/Maybach S-Class table — S 600, 2016 — 33-2412 · checked 2026-09-01
Verified ordering references
- Service replacementK&N 33-2412
  Qty. 1 · Reusable engine air-filter element · catalog-listed
  K&N lists one element for this application; confirm VIN and build date before ordering.
  Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222/Maybach S-Class table — S 600, 2016 — 33-2412 · checked 2026-09-01
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AMG S 63 — Handcrafted 5.5-liter biturbo AMG V8 (577 hp)
K&N 33-2474
Applies to: 2016 · Handcrafted 5.5-liter biturbo AMG V8 (577 hp) · AMG S 63 · Exact 2016 AMG S 63 engine application. Confirm VIN and build date before ordering.
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222/Maybach S-Class table — AMG S 63, 2016 — 33-2474 (two required) · checked 2026-09-01
Verified ordering references
- Service replacementK&N 33-2474
  Qty. 2 · Reusable engine air-filter element · catalog-listed
  K&N lists two elements for this application; confirm VIN and build date before ordering.
  Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222/Maybach S-Class table — AMG S 63, 2016 — 33-2474 (two required) · checked 2026-09-01
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AMG S 65 — Handcrafted 6.0-liter biturbo AMG V12 (621 hp)
K&N 33-2412
Applies to: 2016 · Handcrafted 6.0-liter biturbo AMG V12 (621 hp) · AMG S 65 · Exact 2016 AMG S 65 engine application. Confirm VIN and build date before ordering.
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222/Maybach S-Class table — AMG S 65, 2016 — 33-2412 · checked 2026-09-01
Verified ordering references
- Service replacementK&N 33-2412
  Qty. 1 · Reusable engine air-filter element · catalog-listed
  K&N lists one element for this application; confirm VIN and build date before ordering.
  Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222/Maybach S-Class table — AMG S 65, 2016 — 33-2412 · checked 2026-09-01
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Mercedes-Maybach S 600 — 6.0-liter biturbo V12 (523 hp)
K&N 33-2412
Applies to: 2016 · 6.0-liter biturbo V12 (523 hp) · Mercedes-Maybach S 600 · Exact 2016 Mercedes-Maybach S 600 engine application. Confirm VIN and build date before ordering.
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222/Maybach S-Class table — Mercedes-Maybach S 600, 2016 — 33-2412 · checked 2026-09-01
Verified ordering references
- Service replacementK&N 33-2412
  Qty. 1 · Reusable engine air-filter element · catalog-listed
  K&N lists one element for this application; confirm VIN and build date before ordering.
  Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222/Maybach S-Class table — Mercedes-Maybach S 600, 2016 — 33-2412 · checked 2026-09-01
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S 550 4MATIC — 4.7-liter biturbo V8 (449 hp)
K&N 33-2474
Applies to: 2016 · 4.7-liter biturbo V8 (449 hp) · S 550 4MATIC · Exact 2016 S 550 4MATIC engine application. Confirm VIN and build date before ordering.
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 550 4MATIC, 2016 — 33-2474 (two required) · checked 2026-09-01
Verified ordering references
- Service replacementK&N 33-2474
  Qty. 2 · Reusable engine air-filter element · catalog-listed
  K&N lists two elements for this application; confirm VIN and build date before ordering.
  Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 550 4MATIC, 2016 — 33-2474 (two required) · checked 2026-09-01
  Search this part on Amazon
AMG S 63 — Handcrafted 5.5-liter biturbo AMG V8 (577 hp)
K&N 33-2474
Applies to: 2016 · Handcrafted 5.5-liter biturbo AMG V8 (577 hp) · AMG S 63 · Exact 2016 AMG S 63 engine application. Confirm VIN and build date before ordering.
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222/Maybach S-Class table — AMG S 63, 2016 — 33-2474 (two required) · checked 2026-09-01
Verified ordering references
- Service replacementK&N 33-2474
  Qty. 2 · Reusable engine air-filter element · catalog-listed
  K&N lists two elements for this application; confirm VIN and build date before ordering.
  Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222/Maybach S-Class table — AMG S 63, 2016 — 33-2474 (two required) · checked 2026-09-01
  Search this part on Amazon
AMG S 65 — Handcrafted 6.0-liter biturbo AMG V12 (621 hp)
K&N 33-2412
Applies to: 2016 · Handcrafted 6.0-liter biturbo AMG V12 (621 hp) · AMG S 65 · Exact 2016 AMG S 65 engine application. Confirm VIN and build date before ordering.
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222/Maybach S-Class table — AMG S 65, 2016 — 33-2412 · checked 2026-09-01
Verified ordering references
- Service replacementK&N 33-2412
  Qty. 1 · Reusable engine air-filter element · catalog-listed
  K&N lists one element for this application; confirm VIN and build date before ordering.
  Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W222/Maybach S-Class table — AMG S 65, 2016 — 33-2412 · checked 2026-09-01
  Search this part on Amazon
Spark plugs
Sourced interval available
Applies to: 2016 · M276, M277, M278, M279 · United States
Published interval: 50,000 mi / 80,000 km / 60 months · Gasoline engines; whichever comes first.
Source: Mercedes-Benz USA — 2016 Maintenance Booklet · pages 18–19 — gasoline-engine spark-plug rows · checked 2026-08-05
Mercedes-AMG M157
Applies to: 2016 · M157 · United States
Published interval: 40,000 mi / 64,000 km / 48 months · Whichever comes first.
Source: Mercedes-Benz USA — 2016 Maintenance Booklet · page 18 — AMG spark-plug row · checked 2026-08-05
Engine coolant
Sourced interval available
Applies to: 2016 · M276, M278 · United States
Published interval: 120,000 mi / 192,000 km / 144 months · Whichever comes first.
Source: Mercedes-Benz USA — 2016 Maintenance Booklet · page 19 — coolant row except engines 277/279 · checked 2026-08-05
M277 or M279 main circuit
Applies to: 2016 · M277, M279 · United States
Published interval: 30,000 mi / 48,000 km / 36 months · Main circuit; whichever comes first. Low-temperature circuit remains 120,000 miles/12 years.
Source: Mercedes-Benz USA — 2016 Maintenance Booklet · pages 18–19 — engines 277/279 coolant rows · checked 2026-08-05

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