Fifth generation · W221 · 2007–2013

2011Mercedes-Benz S-Class


Brought Night View Assist and the first S-Class hybrid (S 400 Hybrid, 2010). The two-door flagship continued as the separate CL-Class (C216) during this era.

Fifth generation · W221

2011 Mercedes-Benz S-Class W221 sedan, elevated side view

Photo: “Mercedes-Benz S Class W221 (5827608453).jpg” by nakhon100 / Wikimedia Commons, licensed under CC BY 2.0. Cropped to 16:9.

Start here

What do you need to know?

This page covers the whole 2011 Mercedes-Benz S-Class model year. Choose your task first; exact trims and engines are separated where the factory offered different versions.

Complete, source-verified lineup

Find your exact 2011 S-Class

Start with a family, body style, or engine. Every card opens the facts and maintenance information for that factory version.

7factory configurations
Verified complete for the U.S.-marketHow this lineup was verified

We checked this U.S.-market lineup against period sources for factory sedan, coupe, cabriolet, drivetrain, and powertrain roster represented by the cited exact-year or factory-archive evidence. Every version shown below has its own detail page.

Verified 2026-09-01 from Mercedes-Benz Public Archive — 221-series S-Class model history.

7versions shown
Four-door 4MATIC all-wheel drive luxury sedan

Mercedes-Benz S 350 BlueTEC 4MATIC Automatic

Body
Four-door 4MATIC all-wheel drive luxury sedan
Engine
3.0-liter turbo-diesel V6
Gearbox
7-speed automatic
Built
Regular production
Open exact version
Four-door rear-wheel drive luxury sedan

Mercedes-Benz S 400 HYBRID Automatic

Body
Four-door rear-wheel drive luxury sedan
Engine
3.5-liter V6 with electric motor
Gearbox
7-speed automatic
Built
Regular production
Open exact version
Four-door rear-wheel drive luxury sedan

Mercedes-Benz S 550 Automatic

Body
Four-door rear-wheel drive luxury sedan
Engine
5.5-liter V8
Gearbox
7-speed automatic
Built
Regular production
Open exact version
Four-door 4MATIC all-wheel drive luxury sedan

Mercedes-Benz S 550 4MATIC Automatic

Body
Four-door 4MATIC all-wheel drive luxury sedan
Engine
5.5-liter V8
Gearbox
7-speed automatic
Built
Regular production
Open exact version
Four-door rear-wheel drive luxury sedan

Mercedes-Benz S 600 Automatic

Body
Four-door rear-wheel drive luxury sedan
Engine
5.5-liter twin-turbo V12
Gearbox
5-speed automatic
Built
Regular production
Open exact version
Four-door rear-wheel drive luxury sedan

Mercedes-Benz S 63 AMG Automatic

Body
Four-door rear-wheel drive luxury sedan
Engine
5.5-liter twin-turbo AMG V8
Gearbox
7-speed automatic
Built
Regular production
Open exact version
Four-door rear-wheel drive luxury sedan

Mercedes-Benz S 65 AMG Automatic

Body
Four-door rear-wheel drive luxury sedan
Engine
6.0-liter twin-turbo AMG V12
Gearbox
5-speed automatic
Built
Regular production
Open exact version

The 2011 model year

Overview

The 2011 U.S. W221 range broadened again with the diesel S 350 BlueTEC 4MATIC. The S 63 AMG also moved from the earlier naturally aspirated 6.2-liter V8 to a 5.5-liter twin-turbo AMG V8, making this a critical engine and service-parts boundary.

Specifications

Engines
  • 3.0-liter turbo-diesel V6
  • 3.5-liter V6 with electric motor
  • 5.5-liter V8
  • 5.5-liter twin-turbo V12
  • 5.5-liter twin-turbo AMG V8
  • 6.0-liter twin-turbo AMG V12
Transmissions
7-speed automatic, 5-speed automatic
Body styles
Four-door 4MATIC all-wheel drive luxury sedan, Four-door rear-wheel drive luxury sedan

Year over year

What changed

  • The S 350 BlueTEC 4MATIC added a turbo-diesel, all-wheel-drive configuration.
  • The S 63 AMG changed to the 5.5-liter twin-turbo AMG V8 while the hybrid, S 550 pair, and V12 cars continued.

Worth knowing

Notable

  • A 2010 S 63 engine assumption must not be carried onto the 2011 car; the AMG V8 families differ.

Living with it

Reliability & ownership notes

  • Inspect Airmatic or Active Body Control operation, electronics, cooling-system condition, and documented service history on the individual car; a generation-level reputation is not evidence that every example has a fault.
  • Match filters, fluids, ignition or diesel-service parts, brakes, and transmission service items to the exact engine, drivetrain, build date, and VIN before ordering.

Maintenance & service parts

Keep your 2011 S-Class on the road

Start with the service interval, then match the engine or exact version you own. Order links appear only when a catalog-backed part number is available, and every listing still needs a fitment check.

Service desk

What this car needs & when

Use this as a service-planning checklist for 2011 Mercedes-Benz S-Class. Start with the interval, confirm which engine or configuration you have, then use an exact ordering reference when one is verified.

Service topics
6
Factory intervals
6
Fitment-scoped
6
Exact references
1

Before orderingIdentify your engine, options and build date.Part numbers and sizes can change within one model year. Shopping links appear only for catalog-backed references; still verify the listing against your vehicle before ordering.

Collect

Bring this model year home

Find a scale model using the exact year, make, and model—not a generic generation search.

Sources

  1. Mercedes-Benz Media — factory S-Class history and W126 design/safety chronology
  2. Mercedes-Benz Public Archive — 221-series S-Class model history

Other Fifth generation years

All Fifth generation · W221 years →

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