Fifth generation · W221 · 2007–2013
2011Mercedes-Benz S-Class
Brought Night View Assist and the first S-Class hybrid (S 400 Hybrid, 2010). The two-door flagship continued as the separate CL-Class (C216) during this era.

Photo: “Mercedes-Benz S Class W221 (5827608453).jpg” by nakhon100 / Wikimedia Commons, licensed under CC BY 2.0. Cropped to 16:9.
Start here
What do you need to know?
This page covers the whole 2011 Mercedes-Benz S-Class model year. Choose your task first; exact trims and engines are separated where the factory offered different versions.
Complete, source-verified lineup
Find your exact 2011 S-Class
Start with a family, body style, or engine. Every card opens the facts and maintenance information for that factory version.
Verified complete for the U.S.-marketHow this lineup was verified
We checked this U.S.-market lineup against period sources for factory sedan, coupe, cabriolet, drivetrain, and powertrain roster represented by the cited exact-year or factory-archive evidence. Every version shown below has its own detail page.
Verified 2026-09-01 from Mercedes-Benz Public Archive — 221-series S-Class model history.
Mercedes-Benz S 350 BlueTEC 4MATIC Automatic
- Body
- Four-door 4MATIC all-wheel drive luxury sedan
- Engine
- 3.0-liter turbo-diesel V6
- Gearbox
- 7-speed automatic
- Built
- Regular production
Mercedes-Benz S 400 HYBRID Automatic
- Body
- Four-door rear-wheel drive luxury sedan
- Engine
- 3.5-liter V6 with electric motor
- Gearbox
- 7-speed automatic
- Built
- Regular production
Mercedes-Benz S 550 Automatic
- Body
- Four-door rear-wheel drive luxury sedan
- Engine
- 5.5-liter V8
- Gearbox
- 7-speed automatic
- Built
- Regular production
Mercedes-Benz S 550 4MATIC Automatic
- Body
- Four-door 4MATIC all-wheel drive luxury sedan
- Engine
- 5.5-liter V8
- Gearbox
- 7-speed automatic
- Built
- Regular production
Mercedes-Benz S 600 Automatic
- Body
- Four-door rear-wheel drive luxury sedan
- Engine
- 5.5-liter twin-turbo V12
- Gearbox
- 5-speed automatic
- Built
- Regular production
Mercedes-Benz S 63 AMG Automatic
- Body
- Four-door rear-wheel drive luxury sedan
- Engine
- 5.5-liter twin-turbo AMG V8
- Gearbox
- 7-speed automatic
- Built
- Regular production
Mercedes-Benz S 65 AMG Automatic
- Body
- Four-door rear-wheel drive luxury sedan
- Engine
- 6.0-liter twin-turbo AMG V12
- Gearbox
- 5-speed automatic
- Built
- Regular production
No factory configuration matches those filters.
The 2011 model year
Overview
The 2011 U.S. W221 range broadened again with the diesel S 350 BlueTEC 4MATIC. The S 63 AMG also moved from the earlier naturally aspirated 6.2-liter V8 to a 5.5-liter twin-turbo AMG V8, making this a critical engine and service-parts boundary.
Specifications
- Engines
- 3.0-liter turbo-diesel V6
- 3.5-liter V6 with electric motor
- 5.5-liter V8
- 5.5-liter twin-turbo V12
- 5.5-liter twin-turbo AMG V8
- 6.0-liter twin-turbo AMG V12
- Transmissions
- 7-speed automatic, 5-speed automatic
- Body styles
- Four-door 4MATIC all-wheel drive luxury sedan, Four-door rear-wheel drive luxury sedan
Year over year
What changed
- The S 350 BlueTEC 4MATIC added a turbo-diesel, all-wheel-drive configuration.
- The S 63 AMG changed to the 5.5-liter twin-turbo AMG V8 while the hybrid, S 550 pair, and V12 cars continued.
Worth knowing
Notable
- A 2010 S 63 engine assumption must not be carried onto the 2011 car; the AMG V8 families differ.
Living with it
Reliability & ownership notes
- Inspect Airmatic or Active Body Control operation, electronics, cooling-system condition, and documented service history on the individual car; a generation-level reputation is not evidence that every example has a fault.
- Match filters, fluids, ignition or diesel-service parts, brakes, and transmission service items to the exact engine, drivetrain, build date, and VIN before ordering.
Maintenance & service parts
Keep your 2011 S-Class on the road
Start with the service interval, then match the engine or exact version you own. Order links appear only when a catalog-backed part number is available, and every listing still needs a fitment check.
Service desk
What this car needs & when
Use this as a service-planning checklist for 2011 Mercedes-Benz S-Class. Start with the interval, confirm which engine or configuration you have, then use an exact ordering reference when one is verified.
- Service topics
- 6
- Factory intervals
- 6
- Fitment-scoped
- 6
- Exact references
- 1
Before orderingIdentify your engine, options and build date.Part numbers and sizes can change within one model year. Shopping links appear only for catalog-backed references; still verify the listing against your vehicle before ordering.
Synthetic engine oil and filter
Sourced interval available
Source: Mercedes-Benz USA service-and-warranty library — select 2011 S-Class · PDF page 6 — All Models: synthetic motor oil and filter at every 10,000-mile/one-year increment · checked
Activated-charcoal combination and dust filters
Sourced interval available
Source: Mercedes-Benz USA service-and-warranty library — select 2011 S-Class · PDF page 6 — All Models: activated-charcoal combination filter and dust-filter rows · checked
Brake fluid
Sourced interval available
Source: Mercedes-Benz USA service-and-warranty library — select 2011 S-Class · PDF page 6 — All Models: brake-fluid change at 20,000-mile/two-year increments · checked
Main-circuit coolant
Sourced interval available
Source: Mercedes-Benz USA service-and-warranty library — select 2011 S-Class · PDF page 6 — Specific Model Services: V12 main-circuit coolant at 30,000-mile/3-year increments · checked
Rear-axle oil
Sourced interval available
Source: Mercedes-Benz USA service-and-warranty library — select 2011 S-Class · PDF page 6 — Specific AMG Model Services: rear-axle oil at 2,000 miles, then 30,000-mile/3-year increments · checked
Initial AMG rear-axle service
Source: Mercedes-Benz USA service-and-warranty library — select 2011 S-Class · PDF page 6 — Specific AMG Model Services: initial rear-axle oil change at 2,000 miles · checked
Mercedes-AMG engine air filter
Exact reference available
Source: Mercedes-Benz USA service-and-warranty library — select 2011 S-Class · PDF page 6 — Specific AMG Model Services: engine air filter at 40,000-mile/4-year increments · checked
S 350 BlueTEC 4MATIC — 3.0-liter turbo-diesel V6
K&N 33-2940
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — 3.0L V6 diesel, 2011 — 33-2940 (two required) · checked
Verified ordering references
- Service replacementK&N 33-2940
Qty. 2 · Reusable engine air-filter element · catalog-listed
K&N lists two elements for this application; confirm VIN and build date before ordering.
Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — 3.0L V6 diesel, 2011 — 33-2940 (two required) · checked
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S 400 HYBRID — 3.5-liter V6 with electric motor
K&N 33-2181
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 400 HYBRID, 2011 — 33-2181 (two required) · checked
Verified ordering references
- Service replacementK&N 33-2181
Qty. 2 · Reusable engine air-filter element · catalog-listed
K&N lists two elements for this application; confirm VIN and build date before ordering.
Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 400 HYBRID, 2011 — 33-2181 (two required) · checked
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S 550 — 5.5-liter V8
K&N 33-2474
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 550, 2011 — 33-2474 (two required) · checked
Verified ordering references
- Service replacementK&N 33-2474
Qty. 2 · Reusable engine air-filter element · catalog-listed
K&N lists two elements for this application; confirm VIN and build date before ordering.
Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 550, 2011 — 33-2474 (two required) · checked
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S 550 4MATIC — 5.5-liter V8
K&N 33-2474
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 550 4MATIC, 2011 — 33-2474 (two required) · checked
Verified ordering references
- Service replacementK&N 33-2474
Qty. 2 · Reusable engine air-filter element · catalog-listed
K&N lists two elements for this application; confirm VIN and build date before ordering.
Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 550 4MATIC, 2011 — 33-2474 (two required) · checked
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S 600 — 5.5-liter twin-turbo V12
K&N 33-2412
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 600, 2011 — 33-2412 · checked
Verified ordering references
- Service replacementK&N 33-2412
Qty. 1 · Reusable engine air-filter element · catalog-listed
K&N lists one element for this application; confirm VIN and build date before ordering.
Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 600, 2011 — 33-2412 · checked
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S 63 AMG — 5.5-liter twin-turbo AMG V8
K&N 33-2474
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 63 AMG, 2011 — 33-2474 (two required) · checked
Verified ordering references
- Service replacementK&N 33-2474
Qty. 2 · Reusable engine air-filter element · catalog-listed
K&N lists two elements for this application; confirm VIN and build date before ordering.
Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 63 AMG, 2011 — 33-2474 (two required) · checked
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S 65 AMG — 6.0-liter twin-turbo AMG V12
K&N 33-2412
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 65 AMG, 2011 — 33-2412 · checked
Verified ordering references
- Service replacementK&N 33-2412
Qty. 1 · Reusable engine air-filter element · catalog-listed
K&N lists one element for this application; confirm VIN and build date before ordering.
Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 65 AMG, 2011 — 33-2412 · checked
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