Four-door rear-wheel drive luxury sedan · 5.5-liter twin-turbo M275 V12
2006 Mercedes-Benz S 600 Automatic
Mercedes-Benz's factory model archive identifies this 2006 S 600 sedan with rear-wheel drive; it is separated where drivetrain changes fitment.

Photo: “2006 Mercedes S320 CDi Auto” by Calreyn88 / Wikimedia Commons, licensed under CC BY-SA 4.0. Cropped to 16:9.
Factory configuration
What this model is
- Trim
- S 600
- Body style
- Four-door rear-wheel drive luxury sedan
- Engine
- 5.5-liter twin-turbo M275 V12
- Transmission
- 5-speed automatic
Configuration-specific ownership
Maintenance for this exact configuration
These items are filtered to the engine, transmission, trim, and model-year applicability recorded for this configuration. Broad Amazon category searches are suppressed here; shopping links appear only beside catalog-backed part numbers.
Service desk
What this car needs & when
Use this as a service-planning checklist for 2006 Mercedes-Benz S 600 Automatic. Start with the interval, confirm which engine or configuration you have, then use an exact ordering reference when one is verified.
- Service topics
- 9
- Factory intervals
- 9
- Fitment-scoped
- 9
- Exact references
- 1
Before orderingIdentify your engine, options and build date.Part numbers and sizes can change within one model year. Shopping links appear only for catalog-backed references; still verify the listing against your vehicle before ordering.
Engine oil and filter
Sourced interval available
Source: Mercedes-Benz — 2006 S 600 (W220/M275) MBMS schedule, preserved by Operation CHARM · Service A/B schedules — oil/filter at both services; first A at 10,000 miles/one year · checked
Combination/dust filter
Sourced interval available
Source: Mercedes-Benz — 2006 S 600 (W220/M275) MBMS schedule, preserved by Operation CHARM · Service B schedule — replace combination/dust filter · checked
Automatic-transmission oil and filter
Sourced interval available
Source: Mercedes-Benz — 2006 S 600 (W220/M275) MBMS schedule, preserved by Operation CHARM · Supplemental Service Items — Once at 40,000 miles · checked
Brake fluid
Sourced interval available
Source: Mercedes-Benz — 2006 S 600 (W220/M275) MBMS schedule, preserved by Operation CHARM · Supplemental Service Items — Every 2 Years · checked
Poly-V-belt tensioning device
Sourced interval available
Source: Mercedes-Benz — 2006 S 600 (W220/M275) MBMS schedule, preserved by Operation CHARM · Supplemental Service Items — Every 40,000 miles or 4 Years · checked
Engine air-filter element
Exact reference available
Source: Mercedes-Benz — 2006 S 600 (W220/M275) MBMS schedule, preserved by Operation CHARM · Supplemental Service Items — Every 60,000 miles or 4 Years · checked
S 600 — 5.5-liter twin-turbo M275 V12
K&N 33-2412
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W220 S-Class table — S 600, 2006 — 33-2412 · checked
Verified ordering references
- Service replacementK&N 33-2412
Qty. 1 · Reusable engine air-filter element · catalog-listed
K&N lists one element for this application; confirm VIN and build date before ordering.
Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W220 S-Class table — S 600, 2006 — 33-2412 · checked
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Fuel filter
Sourced interval available
Source: Mercedes-Benz — 2006 S 600 (W220/M275) MBMS schedule, preserved by Operation CHARM · Supplemental Service Items — Every 60,000 miles or 5 Years · checked
Spark plugs
Sourced interval available
Source: Mercedes-Benz — 2006 S 600 (W220/M275) MBMS schedule, preserved by Operation CHARM · Supplemental Service Items — Every 60,000 miles or 5 Years · checked
Low-temperature-circuit coolant
Sourced interval available
Source: Mercedes-Benz — 2006 S 600 (W220/M275) MBMS schedule, preserved by Operation CHARM · Supplemental Service Items — Every 150,000 miles or 15 Years · checked
Sources
Other 2006 configurations