Four-door rear-wheel drive luxury sedan · 3.7-liter M112 V6
2006 Mercedes-Benz S 350 Automatic
Mercedes-Benz's factory model archive identifies this 2006 S 350 sedan with rear-wheel drive; it is separated where drivetrain changes fitment.

Photo: “2006 Mercedes S320 CDi Auto” by Calreyn88 / Wikimedia Commons, licensed under CC BY-SA 4.0. Cropped to 16:9.
Factory configuration
What this model is
- Trim
- S 350
- Body style
- Four-door rear-wheel drive luxury sedan
- Engine
- 3.7-liter M112 V6
- Transmission
- 5-speed automatic
Compare related 2006 configurations
Compare up to twelve documented pairings, prioritizing the same engine, body, trim and gearbox as this car. This related selection is not a complete factory lineup.
Browse all documented 2006 configurations →
Compare 8 related configurations — current car marked
| Configuration | Engine | Transmission | Body |
|---|---|---|---|
| Current carMercedes-Benz S 350 Automatic | 3.7-liter M112 V6 | 5-speed automatic | Four-door rear-wheel drive luxury sedan |
| Mercedes-Benz S 430 Automatic | 4.3-liter M113 V8 | 7-speed automatic | Four-door rear-wheel drive luxury sedan |
| Mercedes-Benz S 430 4MATIC Automatic | 4.3-liter M113 V8 | 5-speed automatic | Four-door 4MATIC all-wheel drive luxury sedan |
| Mercedes-Benz S 500 Automatic | 5.0-liter M113 V8 | 7-speed automatic | Four-door rear-wheel drive luxury sedan |
| Mercedes-Benz S 500 4MATIC Automatic | 5.0-liter M113 V8 | 5-speed automatic | Four-door 4MATIC all-wheel drive luxury sedan |
| Mercedes-Benz S 55 AMG Automatic | 5.4-liter supercharged AMG V8 | 5-speed automatic | Four-door rear-wheel drive luxury sedan |
| Mercedes-Benz S 600 Automatic | 5.5-liter twin-turbo M275 V12 | 5-speed automatic | Four-door rear-wheel drive luxury sedan |
| Mercedes-Benz S 65 AMG Automatic | 6.0-liter twin-turbo AMG V12 | 5-speed automatic | Four-door rear-wheel drive luxury sedan |
Configuration-specific ownership
Maintenance for this exact configuration
These items are filtered to the engine, transmission, trim, and model-year applicability recorded for this configuration. Broad Amazon category searches are suppressed here; shopping links appear only beside catalog-backed part numbers.
Service desk
What this car needs & when
Use this as a service-planning checklist for 2006 Mercedes-Benz S 350 Automatic. Start with the interval, confirm which engine or configuration you have, then use an exact ordering reference when one is verified.
- Service topics
- 1
- Scheduled topics
- 0
- Applicability stated
- 1
- Exact references
- 1
Before ordering Identify your engine, options and build date. Part numbers and sizes can change within one model year. Shopping links appear only for catalog-backed references; still verify the listing against your vehicle before ordering.
Engine air-filter elementView intervals, applicability and sources
Engine air-filter element
Exact reference available
S 350 — 3.7-liter M112 V6
K&N 33-2181
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W220 S-Class table — S 350, 2006 — 33-2181 (two required) · checked
Verified ordering references
- Service replacementK&N 33-2181
Qty. 2 · Reusable engine air-filter element · catalog-listed
K&N lists two elements for this application; confirm VIN and build date before ordering.
Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W220 S-Class table — S 350, 2006 — 33-2181 (two required) · checked
Search this part on Amazon
Search results may cover different scales, trims and model years. Check each listing; this search does not establish an exact replica of the documented vehicle.
Sources
Other 2006 configurations