Four-door rear-wheel drive luxury sedan · 6.0-liter twin-turbo AMG V12
2010 Mercedes-Benz S 65 AMG Automatic
Mercedes-Benz's factory model archive identifies this 2010 S 65 AMG sedan with rear-wheel drive; it is separated where drivetrain changes fitment.

Photo: “'10 Mercedes-Benz S-Class (MIAS '10).jpg” by Bull-Doser / Wikimedia Commons — Public domain. Cropped to 16:9.
Factory configuration
What this model is
- Trim
- S 65 AMG
- Body style
- Four-door rear-wheel drive luxury sedan
- Engine
- 6.0-liter twin-turbo AMG V12
- Transmission
- 5-speed automatic
Compare related 2010 configurations
Compare up to twelve documented pairings, prioritizing the same engine, body, trim and gearbox as this car. This related selection is not a complete factory lineup.
Browse all documented 2010 configurations →
Compare 6 related configurations — current car marked
| Configuration | Engine | Transmission | Body |
|---|---|---|---|
| Mercedes-Benz S 400 HYBRID Automatic | 3.5-liter V6 with electric motor | 7-speed automatic | Four-door rear-wheel drive luxury sedan |
| Mercedes-Benz S 550 Automatic | 5.5-liter V8 | 7-speed automatic | Four-door rear-wheel drive luxury sedan |
| Mercedes-Benz S 550 4MATIC Automatic | 5.5-liter V8 | 7-speed automatic | Four-door 4MATIC all-wheel drive luxury sedan |
| Mercedes-Benz S 600 Automatic | 5.5-liter twin-turbo V12 | 5-speed automatic | Four-door rear-wheel drive luxury sedan |
| Mercedes-Benz S 63 AMG Automatic | 6.2-liter AMG V8 | 7-speed automatic | Four-door rear-wheel drive luxury sedan |
| Current carMercedes-Benz S 65 AMG Automatic | 6.0-liter twin-turbo AMG V12 | 5-speed automatic | Four-door rear-wheel drive luxury sedan |
Configuration-specific ownership
Maintenance for this exact configuration
These items are filtered to the engine, transmission, trim, and model-year applicability recorded for this configuration. Broad Amazon category searches are suppressed here; shopping links appear only beside catalog-backed part numbers.
Service desk
What this car needs & when
Use this as a service-planning checklist for 2010 Mercedes-Benz S 65 AMG Automatic. Start with the interval, confirm which engine or configuration you have, then use an exact ordering reference when one is verified.
- Service topics
- 3
- Scheduled topics
- 3
- Applicability stated
- 3
- Exact references
- 1
Before ordering Identify your engine, options and build date. Part numbers and sizes can change within one model year. Shopping links appear only for catalog-backed references; still verify the listing against your vehicle before ordering.
Brake fluidView intervals, applicability and sources
Brake fluid
Sourced interval available
Source: Mercedes-Benz USA — 2010 Maintenance Booklet · page 16 and subsequent even-year services — replace brake fluid · checked
Combination or dust filterView intervals, applicability and sources
Combination or dust filter
Sourced interval available
Source: Mercedes-Benz USA — 2010 Maintenance Booklet · page 16 and subsequent even-year services — combination/dust-filter row · checked
Engine air filterView intervals, applicability and sources
Engine air filter
Exact reference available
Source: Mercedes-Benz USA — 2010 Maintenance Booklet · page 61 — 120,000-mile/12-year air-filter row · checked
S 65 AMG — 6.0-liter twin-turbo AMG V12
K&N 33-2412
Source: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 65 AMG, 2010 — 33-2412 · checked
Verified ordering references
- Service replacementK&N 33-2412
Qty. 1 · Reusable engine air-filter element · catalog-listed
K&N lists one element for this application; confirm VIN and build date before ordering.
Catalog: K&N Engineering — 2017 European Automotive Catalog, S-Class application tables (archived copy) · W221 S-Class table — S 65 AMG, 2010 — 33-2412 · checked
Search this part on Amazon
Search results may cover different scales, trims and model years. Check each listing; this search does not establish an exact replica of the documented vehicle.
Sources
Other 2010 configurations