Four-door all-wheel-drive sedan · 3.0-liter turbo inline-six mild hybrid
2022 Mercedes-Benz S 500 4MATIC Sedan
Mercedes-Benz USA's 2022 warranty model matrix explicitly lists the S 500 4MATIC Sedan as a U.S. model. Output figures are intentionally omitted because this source establishes applicability rather than specifications.

Photo: “Mercedes-Benz S-Klasse (W223) S 580 4MATIC (2022) (52921615957)” by Charles from Port Chester, New York / Wikimedia Commons, licensed under CC BY 2.0. Cropped to 16:9.
Factory configuration
What this model is
- Trim
- S 500 4MATIC
- Body style
- Four-door all-wheel-drive sedan
- Engine
- 3.0-liter turbo inline-six mild hybrid
- Transmission
- 9G-TRONIC 9-speed automatic
Configuration-specific ownership
Maintenance for this exact configuration
These items are filtered to the engine, transmission, trim, and model-year applicability recorded for this configuration. Broad Amazon category searches are suppressed here; shopping links appear only beside catalog-backed part numbers.
Service desk
What this car needs & when
Use this as a service-planning checklist for 2022 Mercedes-Benz S 500 4MATIC Sedan. Start with the interval, confirm which engine or configuration you have, then use an exact ordering reference when one is verified.
- Service topics
- 4
- Factory intervals
- 2
- Fitment-scoped
- 4
- Exact references
- 1
Before orderingIdentify your engine, options and build date.Part numbers and sizes can change within one model year. Shopping links appear only for catalog-backed references; still verify the listing against your vehicle before ordering.
Cabin dust/combination filter
Sourced interval available
Source: Mercedes-Benz USA — current Service A and Service B intervals · Service Intervals — Service B: cabin dust/combination filter replacement · checked
Brake fluid
Sourced interval available
Source: Mercedes-Benz USA — current Service A and Service B intervals · Service Intervals — Service B: brake-fluid exchange · checked
Engine air filter
Exact reference available
The part reference below is catalog fitment only; retain the separately sourced factory service interval where one is shown.
S 500 4MATIC — 3.0-liter turbo inline-six mild hybrid
K&N 33-3068
Source: K&N Engineering — Mercedes-Benz S-Class replacement-air-filter application catalog · 2022 Mercedes-Benz S500 3.0L inline-six Gas — 33-3068 · checked
Verified ordering references
- Service replacementK&N 33-3068
Qty. 1 · Reusable engine air-filter element · catalog-listed
K&N lists one element for this application; confirm VIN and build date before ordering.
Catalog: K&N Engineering — Mercedes-Benz S-Class replacement-air-filter application catalog · 2022 Mercedes-Benz S500 3.0L inline-six Gas — 33-3068 · checked
Search this part on Amazon
Engine oil filter
Fitment must be confirmed
Use the exact engine, VIN, and build date to confirm the catalogued service part before ordering.
Sources
Other 2022 configurations